Telomeres and Telomerase in Aging, Disease, and Cancer
Author | : K. Lenhard Rudolph |
Publisher | : Springer Science & Business Media |
Total Pages | : 332 |
Release | : 2007-11-07 |
ISBN-13 | : 9783540737094 |
ISBN-10 | : 354073709X |
Rating | : 4/5 (9X Downloads) |
Download or read book Telomeres and Telomerase in Aging, Disease, and Cancer written by K. Lenhard Rudolph and published by Springer Science & Business Media. This book was released on 2007-11-07 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Telomere shortening represents one of the basic aspects of ageing and telomere dysfunction could contribute to the accumulation of DNA damage during ageing. This book summarizes evidence and data indicating that telomere dysfunction influences human ageing, diseases and cancer. The book describes our current knowledge on checkpoints that limit cellular lifespan and survival in response to telomere dysfunction. There is special focus on adult stem cells.