The continued successes of large- and small-scale genome sequencing projects are increasing the number of genomic targets available for drug d- covery at an exp

Research in the pharmaceutical industry today is in many respects quite different from what it used to be only fifteen years ago. There have been dramatic chang

Protein-protein interactions (PPI) are at the heart of the majority of cellular processes, and are frequently dysregulated or usurped in disease. Given this cen

This text traces developments in rational drug discovery and combinatorial library design with contributions from 50 leading scientists in academia and industry

This book addresses the various classes of privileged scaffolds and covers the history of their discovery and use.